Five Skin Problems That Are Inherited

Skin is actually tough and is also spread over a large area, in spite of these things there many problems that seem to affect skin. UV radiation from sun can cause harm to the DNA in the cells of the skin and this could lead to burnt skin and also cancer. On the other hand windy and dry weather can take away from moisture from the skin making it chapped and painful. What is more the sebaceous glands tend to be get clogged which can result in acne.

Some steps that we take can help keep the harm caused to skin to a minimum, however there are some skin problems that are genetic and occur from within. The skin problems that are inherited are called genondermatoses. The range is huge under this group and different conditions need to be treated differently. Here we give five skin problems that are inherited and this covers plenty of epidermis.

Darier White Disease 2

Darier-White Disease: Also called keratosis follicularis was first found in the later part of the 19th century and was found by James Clarke White and Ferdinand-Jena Darier who were dermatologists. The disease was identified by White when a mother- daughter duo came to him for treatment. The symptoms of this condition are skin cells that harden on the skin outer layer. This is known as keratinization which is also the process that makes normal skin into fingernails. However, with people having this condition, this happens all over the body. Research has shown the people with Darier-White disease don’t have the junction that binds cells with each other and this makes keratinization happen often. The most commonly seen symptom is yellow brown papules that are similar to pimple and are brownish yellow. These form in groups under the sebaceous glands.

Epidermolysis Bullosa

Epidermolysis Bullosa: This is a skin disorder that weakens you as it makes the skin to blister from the smallest changes in temperature or pressure. In normal conditions people get a blister in response to the outer layer of the skin getting separated from the inner layer as the area that is in between fills with fluid providing a cushion till the healing of the injured skin takes place. Folks having EB will have more blister respons that could result from simple activities like walking, being held, crawling or even small changes in the temperature. With blistering becoming more frequent, patients could also have an infection leading to more complications. In general a mutation on gene that is responsible for offering strength and structure to bind the skin layers is inherited from ones parents.

Lamellar Ichthyosis

Lamellar Ichthyosis: This condition derives from the Latin term for fish as people with this condition can develop scales on the skin. In people with normal health, the older skins will protect the younger cells before being shed and replaced. Under the outer layer skin cells called keratinocytes divide to make new cells that are healthy. Once they age, these cells will become hard and migrate to the stratum corneum to make a barrier that protects. They are shed when new cells that are hardened take their place. People with lamellar ichthyosis will find that as the older cells harden and migrate they do not separate and this stops them from being shed leading to the formation of scaly plates that are hard. This is a rare condition.

Cutaneous Porphyria 2

Cutaneous Porphyria: This is really a collection of 6 types of disorders that are inherited porphyria. Patients with these problem have the inability to create enzymes that make heme which is a component for red blood cells that are instrumental in delivering oxygen. Heme is composed of chemical, porphyrins which can collect when they don’t convert to heme and the lack of heme leads to porphyria.

With cutaneous porphyria a person’s skin becomes really sensitive and becomes red, blistered and irritated when exposed to the sun. The skin could also swell a lot when exposed to sun.

Mal de Meleda

Mal de Meleda: This one is pretty rare and is found chiefly from folks of Mediterranean descent and has been named after the island of Meleda. It is a type of Keratosis Palmaris et Plantaris, the main symptom of which is thickening of the skin on soles and palms, which is due to the increase in the size of skin cells. It also turns them to yellow color. This is a rare condition and for a person to get this they have to have two copies of the mutated gene from each parent.